@conference {78979,
	title = {Associations of uterine pathology with milk production and effects of treatment with a nonsteroidal anti-inflammatory drug in dairy cows},
	booktitle = {Proceedings of the New Zealand Society of Animal Production},
	volume = {72},
	year = {2012},
	month = {Jan},
	pages = {23-27},
	publisher = {New Zealand Society of Animal Production},
	organization = {New Zealand Society of Animal Production},
	address = {Christchurch},
	abstract = {<p>Subclinical endometritis (SCE) is a form of uterine pathology characterised by an increased proportion of polymorphonuclear cells (PMN) in the uterus post-calving. Previous studies demonstrated a negative association between SCE and lower milk production, with indications that systemic inflammation underlies this link. Accordingly, the hypothesis tested was that treatment with a non-steroidal antiinflammatory drug (NSAID) would increase milk yield in cows with >= 14\% PMN at Day 14. In this study, >= 14\% PMN in the cytological sample collected at Day 14 postpartum was defined as SCE. To test this hypothesis, 213 dairy cows were paired by calving date and Day 14 PMN\%, then randomly assigned to three doses of a NSAID (Carprofen 1.4 mg/kg, n = 103) between 21 and 31 days postpartum or left as untreated controls (n = 108). The effect of the NSAID treatment on milk production was analysed using mixed models. While the results supported previous evidence of a negative association between SCE and milk production, NSAID had no effect on either PMN \% at Day 42 or milk production (P \&gt; 0.1) in this study. The lack of a NSAID effect was possibly because SCE spontaneously resolved in more than 90\% of the cases</p>
},
	issn = {1176-5283},
	author = {Priest NV and McLeod KLM and McDougall S and Burke CR and Roche JR and Mitchell M and Greenwood SL}
}
